Fig. 2

DEGs dentification among three GEO datasets. A Volcano plots of DEGs in the three datasets (GEO8671, GEO15960 and GEO37364). There were 2252 DEGs in GSE8671, including 918 upregulated and 1334 downregulated genes; 2992 DEGs in GSE15960, including 1487 upregulated and 1505 downregulated genes; 1598 DEGs in GSE37364, including 777 upregulated and 821 downregulated genes. Red, upregulation; blue, downregulation; grey, none significance. B Heatmap of the top 200 DEGs (100 up and 100 down-regulated genes) among the datasets. C Venn diagrams of DEGs among the three GEO datasets with the same trends. The overlap included 127 upregulated and 103 downregulated genes