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Table 2 Associations between dementia status and diagnoses of unstaged or advanced-stage cancer in older adults

From: Patterns of staging, treatment, and mortality in gastric, colorectal, and lung cancer among older adults with and without preexisting dementia: a Japanese multicentre cohort study

 

Model 1: Adjusted odds ratios of being diagnosed with unstaged cancer

 

Gastric cancer (n = 6016)

Colorectal cancer (n = 7257)

Lung cancer (n = 4502)

 

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

No dementia

Reference

 

Reference

 

Reference

 

Mild dementia

1.38 (0.61–3.10)

0.442

3.63 (1.81–7.27)

< 0.001

2.62 (1.30–5.27)

0.007

Moderate-to-severe dementia

5.27 (2.55–10.91)

< 0.001

6.35 (2.52–16.05)

< 0.001

7.47 (3.49–16.01)

< 0.001

 

Model 2: Adjusted odds ratios of being diagnosed with advanced-stage cancera

 

Gastric cancer (n = 5920)

Colorectal cancer (n = 7196)

Lung cancer (n = 4426)

 

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

No dementia

Reference

 

Reference

 

Reference

 

Mild dementia

1.49 (1.13–1.97)

0.005

1.47 (1.15–1.87)

0.002

1.40 (1.01–1.95)

0.043

Moderate-to-severe dementia

1.79 (1.10–2.89)

0.019

3.14 (1.85–5.30)

< 0.001

3.78 (1.70–8.40)

0.001

  1. All odds ratios are adjusted for age, sex, and comorbidities. Model 2 only included patients who received cancer staging
  2. CI confidence interval
  3. aAdvanced stage includes stages II, III, and IV