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Table 2 Association between PINI and disease-free survival of patients with colorectal cancer

From: Prognostic significance of preoperative prognostic immune and nutritional index in patients with stage I–III colorectal cancer

PINI

Model a

P value

Model b

P value

Model c

P value

Continuous (per SD)

0.845 (0.784,0.912)

< 0.001

0.827 (0.763,0.897)

< 0.001

0.823 (0.754,0.898)

< 0.001

Cutoff value

 

< 0.001

 

< 0.001

 

< 0.001

 C1 (~ 2.85)

ref

 

ref

 

ref

 

 C2 (2.85~)

0.618 (0.513,0.743)

 

0.605 (0.500,0.733)

 

0.587 (0.477,0.722)

 

Quartiles

      

 Q1 (~ 2.84)

ref

 

ref

 

ref

 

 Q2 (2.84 ~ 3.15)

0.664 (0.526,0.84)

0.001

0.632 (0.498,0.802)

< 0.001

0.619 (0.484,0.793)

< 0.001

 Q3 (3.15 ~ 3.38)

0.617 (0.484,0.786)

< 0.001

0.639 (0.498,0.819)

< 0.001

0.603 (0.464,0.783)

< 0.001

 Q4 (3.38~)

0.582 (0.454,0.746)

< 0.001

0.558 (0.432,0.719)

< 0.001

0.542 (0.412,0.711)

< 0.001

p for trend

 

< 0.001

 

< 0.001

 

< 0.001

  1. Model a: No adjusted
  2. Model b: Adjusted for sex, age, T stage and N stage
  3. Model c: Adjusted for sex, age, BMI, hypertension, diabetes, T stage, N stage, tumor location, tumor size, perineural invasion, vascular invasion, macroscopic type, differentiation, surgical approach, CEA level, radiotherapy, and chemotherapy