Table 3 Model performance after the addition of each biomarker to the TNM stage for predicting all-cause mortality

TNM stage

0.664(0.653,0.674)

 < 0.001

Ref

Ref

TNM stage + INS

0.717(0.706,0.728)

 < 0.001

0.273(0.225,0.323)

 < 0.001

0.035(0.022,0.048)

 < 0.001

TNM stage + LCR

0.694(0.684,0.705)

 < 0.001

0.306(0.259,0.353)

 < 0.001

0.030(0.019,0.042)

 < 0.001

TNM stage + CAR

0.693(0.683,0.704)

 < 0.001

0.293(0.247,0.335)

 < 0.001

0.028(0.018,0.040)

 < 0.001

TNM stage + ALI

0.693(0.682,0.704)

 < 0.001

0.230(0.184,0.278)

 < 0.001

0.014(0.005,0.023)

 < 0.001

TNM stage + NRI

0.688(0.677,0.699)

 < 0.001

0.144(0.096,0.183)

 < 0.001

0.010(0.002,0.018)

0.014

TNM stage + mGNRI

0.700(0.689,0.712)

 < 0.001

0.227(0.172,0.283)

 < 0.001

0.036(0.022,0.052)

 < 0.001

TNM stage + NLR

0.696(0.685,0.708)

 < 0.001

0.127(0.024,0.211)

 < 0.001

0.003(0.001,0.005)

 < 0.001

TNM stage + mGPS

0.697(0.686,0.709)

 < 0.001

0.266(0.225,0.300)

 < 0.001

0.023(0.014,0.031)

 < 0.001

TNM stage + SII

0.691(0.680,0.703)

 < 0.001

0.079(-0.064,0.158)

0.189

0.004(0.001,0.007)

0.010

TNM stage + LCS

0.688(0.677,0.699)

 < 0.001

0.336(0.278,0.382)

0.010

0.030(0.020,0.040)

 < 0.001

TNM stage + GLR

0.683(0.671,0.694)

 < 0.001

0.068(-0.015,0.193)

0.080

0.000(0.000,0.001)

0.109

TNM stage + PLR

0.680(0.669,0.692)

 < 0.001

0.023(-0.339,0.078)

0.507

0.001(-0.001,0.004)

0.259

TNM stage + PNI

0.700(0.688,0.711)

 < 0.001

0.084(0.025,0.136)

0.010

0.012(0.003,0.021)

 < 0.001

TNM stage + GNRI

0.702(0.690,0.713)

 < 0.001

0.124(0.063,0.166)

 < 0.001

0.019(0.009,0.029)

 < 0.001

TNM stage + AGR

0.693(0.681,0.704)

 < 0.001

0.120(0.060,0.162)

 < 0.001

0.019(0.009,0.031)

 < 0.001

TNM stage + CONUT

0.694(0.683,0.705)

 < 0.001

0.016(-0.030,0.062)

0.338

0.009(0.004,0.015)

0.010