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Fig. 3 | BMC Cancer

Fig. 3

From: Downstaging and survival after Neoadjuvant chemotherapy for bladder cancer in Norway; a population-based study

Fig. 3

Summary of results. Summary of the results; logistic regression (1), Cox regression (2-3) and mediation analysis (4–5). (1) Neoadjuvant chemotherapy (NAC) is significantly associated with pathological downstaging (DS: ≤pT1), (2) DS is significantly associated with overall survival (OS), (3) NAC is not significantly associated with OS (unadjusted for DS) (Total effect), (4) NAC is not significantly associated with OS (not through DS) (Direct effect), (5) NAC is significantly associated with OS through DS (Indirect effect) (red arrow: significant; the thicker, the more significant; blue arrow: not significant). *All analyses were adjusted for age, sex, type of hospital, health region and cystectomy year

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