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Fig. 4 | BMC Cancer

Fig. 4

From: Transcription factor c-Jun modulates GLUT1 in glycolysis and breast cancer metastasis

Fig. 4

Relation of GLUT1 to Mutations, Methylation and Copy Number Alterations in Breast Cancer. a Mutations in 33 types of cancer. Altered in 195 (2%) of 10,967 sequenced patiens (10,967 total) from TCGA PanCancer Atlas Studies (cBioPortal web tool). b Mutations in breast cancer. Altered in 65 (6%) of 1108 sequenced patiens (1108 total) from TCGA, Firehose Legacy (cBioPortal web tool). c Methylation level using spearman (r = − 0.46, p = 1.21e− 12) and pearson (r = − 0.43, p = 5.53e− 11) from TCGA, Firehose Legacy (cBioPortal web tool). d Copy number alterations from TCGA, Firehose Legacy (cBioPortal web tool). SD: Shallow Deletion, D: Diploid, G: Gain, A: Amplification. e and f Heatmap of top [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25] genes with hyper and hypo methylated promoters, respectively (UALCAN database)

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