Table 4 Top statistically significant Gene Ontology molecular functions

CD HCC vs. NASH

Hormone binding

3.05

DNA-binding transcription activator activity, RNA polymerase II-specific

1.88

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1.72

Calcium ion binding

1.57

CS HCC vs. NASH

Neuropeptide receptor activity

2.76

Voltage-gated potassium channel activity

2.03

DNA-binding transcription activator activity, RNA polymerase II-specific

1.61

DNA binding transcription repressor activity, RNA polymerase-II specific

1.5

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1.49

Signaling receptor activator activity

1.39