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Fig. 1 | BMC Cancer

Fig. 1

From: Development of an integrated predictive model for postoperative glioma-related epilepsy using gene-signature and clinical data

Fig. 1

Identification and functional enrichment analysis of differentially expressed genes (DEGs) associated with preoperative glioma-related epilepsy (GRE). A, Volcano plot of DEGs identified based on adjusted p < 0.05 and |log2fc|≥ 0.8. (B-F), functional enrichment analysis of DEGs: B-C, Gene ontology (GO) terms associated with upregulated and downregulated genes; D-F, Enriched molecular functions and pathways associated with preoperative GRE history based on gene set enrichment analysis (GSEA). G-H, Distribution of 22 immune cells in the training cohort, and differences in tumor microenvironment (TME) cell compositions of patients with and without preoperative GRE

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