Fig. 5

Notch signaling pathway gene expression pattern in breast cancer and normal tissues. RNA-Seq mRNA expression data for breast cancer (red color) and normal (blue in color) subtypes in METABRIC cohort. Normal (Normal-like) samples (n = 148) and cancer tissues (all subtypes), (n = 1826) of primary breast tumors have been used. Data were analyzed by an unpaired t-test between cancer and normal group for each single gene. Statistically significant values of *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 were determined