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Table 1 Pre- and post-treatment evaluation and assessment of efficacy

From: Daily irradiation versus irradiation at two- to three-day intervals in stereotactic radiotherapy for patients with 1-5 brain metastases: study protocol for a multicenter open-label randomized phase II trial

 

Baseline

Treatment

Follow-up after

Assessmenta

  

1 M

3 M

6 M

Every 3 M thereafter

Every 6 M thereafter

Medical history

      

Physical examination

 

 

CT or PET-CTb

      

KPS

 

 

JCS

 

 

MMSE

   

 

Brain MRI

 

 

Adverse events

 

 
  1. Footnotes: M Months, CT Computed tomography, PET-CT 18F-fluorodeoxyglucose positron emission tomography-computed tomography, KPS Karnofsky performance status, JCS Japan Coma Scale, MMSE Mini mental status examination, MRI Magnetic resonance imaging
  2. aExtra imaging outside of the study schedule is allowed per the discretion of the physician
  3. bEither enhanced CT or PET-CT is required