Genetic variant in miR-17-92 cluster binding sites is associated with esophageal squamous cell carcinoma risk in Chinese population

Table 1 Demographic characteristics of ESCC patients and controls

Variables	Cases (%)	Controls (%)	P	OR (95%CI)
Variables	n = 488	n = 512	P	OR (95%CI)
Age (mean ± SD), year	63.04 ± 7.09	62.89 ± 4.25	0.682^a
Gender
Female	152 (31.1)	207 (40.4)	0.002^b	1.000
Male	336 (68.9)	305 (59.6)		1.500 (1.156–1.947)
Smoking status
Never	262 (53.7)	379 (74.0)	< 0.001^b	1.000
Current/former	226 (46.3)	133 (26.0)		2.458 (1.884–3.207)
Family history of cancers
No	278 (57.0)	286 (55.9)	0.724^b	1.000
Yes	210 (43.0)	226 (44.1)		0.956 (0.744–1.228)

^aP-value for Student’s t-test; ^bP-value for a two-sided χ² test; CI Confidence interval, OR odds ratio, SD Standard deviation

ISSN: 1471-2407