Table 3 Univariate and multivariate analysis of the potential prognostic laboratory markers with primary site

HR (95% CI)

P

HR (95% CI)

P

 Slow growth

Ref

Ref

Ref

 Moderate growth

2.376 (1.525–3.703)

< 0.001*

1.942 (1.230–3.069)

0.004**

 Rapid growth

3.396 (2.278–5.061)

< 0.001*

2.988 (1.975–4.520)

< 0.001**

WBC

1.074 (1.024–1.125)

0.003*

1.285 (1.086–1.520)

0.004**

Hemoglobin

0.820 (0.747–0.900)

< 0.001*

0.992 (0.982–1.001)

0.914

Platelet

1.000 (0.997–1.002)

0.641

Lymphocyte count

0.663 (0.526–0.835)

< 0.001*

0.511 (0.322–0.809)

0.004**

Neutrophil count

1.098 (1.044–1.154)

< 0.001*

0.835 (0.678–1.029)

0.091

Albumin

0.385 (0.273–0.541)

< 0.001*

0.501 (0.342–0.734)

< 0.001**

Alkaline phosphatase

1.000 (0.999–1.001)

0.825

Creatinine

2.082 (0.984–4.405)

0.055*

2.126 (1.006–4.491)

0.048**

Total Bilirubin

0.992 (0.962–1.022)

0.581

Ca2+

1.103 (0.916–1.327)

0.302

INR

3.662 (1.647–8.143)

0.001*

1.373 (0.482–3.914)

0.553

NLR

1.048 (1.020–1.077)

< 0.001*

0.962 (0.888–1.043)

0.352

PLR

1.001 (1.000–1.002)

0.009*

1.000 (0.999–1.002)

0.650