Early prediction of pathological complete response to neoadjuvant chemotherapy combining DCE-MRI and apparent diffusion coefficient values in breast Cancer

Table 3 Comparison of post-NAC DCE-MRI parameters and ADC values between pCR and the non pCR group

Groups	N	K^trans† (min^-1)	K_ep^† (min^-1)	V_e^† (%)	IAUC^†	ADC^†	W-in^†	W-out^†	TTP^†
Non pCR	95	0.13 (0.08, 0.19)	0.48 (0.31, 0.74)	0.24 (0.19, 0.36)	0.15 (0.09, 0.22)	0.94 (0.84, 1.15)	0.26 (0.13, 0.43)	0.00(-0.01, 0.02)	0.72 (0.58, 1.03)
pCR	24	0.03 (0.01, 0.06)	0.14 (0.07, 0.42)	0.23 (0.15, 0.39)	0.04 (0.02, 0.07)	1.13 (1.04, 1.32)	0.05 (0.03, 0.09)	0.01(-0.00, 0.02)	0.91 (0.79, 2.33)
P Value		<0.001^b*	<0.001^b*	0.527^b	<0.001^b*	0.001^b*	<0.001^b*	0.276^b	0.001^b*

Note:^†Results are the median with interquartile range in parentheses. P^b: Mann–Whitney U test. *P value <0.05, indicating that the differences were considered statistically significant. Abbreviations: N Number, pCR Pathologic complete response

ISSN: 1471-2407