Variable | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | pa | HR (95% CI) | pa | |
Age (≥ 60/<  60) | 0.759 (0.397-1.453) | 0.406 |  |  |
Gender (Male/Female) | 0.880 (0.402-1.926) | 0.748 | Â | Â |
Location (Cardia/Fundus/ Antrum/Other) | 1.103 (0.762-1.597) | 0.603 | Â | Â |
Tumor mass size (≥ 5/<  5) | 1.384 (0.694-2.759) | 0.356 |  |  |
Histologic grade (Poor, Undifferented /Good, mod) | 1.002 (0.452-2.224) | 0.996 | Â | Â |
Tumor depth (T3, T4/T1, T2) | 1.267 (0.579-2.774) | 0.554 | Â | Â |
Vascular invasion (Present/Absent) | 2.562 (1.262-5.204) | 0.009 | Â | Â |
Nervous invasion (Present/Absent) | 1.530 (0.792-2.954) | 0.206 | Â | Â |
Lymphatic metastasis (Present/Absent) | 3.620 (1.406-9.317) | 0.008 | 3.205 (1.237-8.305) | 0.017 |
pTNM stage (III + IV/I + II) | 1.780 (0.914-3.466) | 0.090 |  |  |
FOXM1 protein (High/Low) | 1.075 (0.563-2.053) | 0.827 | Â | Â |
FAP protein (High/Low) | 2.534 (1.311-4.899) | 0.006 | 2.218 (1.145-4.297) | 0.018 |
EZH2 protein (High/Low) | 2.646 (0.811-8.625) | 0.107 | Â | Â |