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Fig. 8 | BMC Cancer

Fig. 8

From: CX3CL1 promotes cell sensitivity to ferroptosis and is associated with the tumor microenvironment in clear cell renal cell carcinoma

Fig. 8

CX3CL1 inhibits ccRCC proliferation by inducing ferroptosis in vivo. A The representative images of xenografts in nude mice. B–C Tumor growth and weights of xenograft tumors from normal control and OE-CX3CL1 786-O cells. D Western blotting of CX3CL1, PCNA, GPX4, and XCT proteins. E The immunostaining assay identified the CX3CL1, GPX4, and PCNA proteins’ localization in xenografts tumors. F-G Representative images and quantitative analysis of CX3CL1, GPX4, and PCNA by IHC assay. Scale bar: 50 μm. *P < 0.05, **P < 0.01, ***P < 0.001

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BMC Cancer

ISSN: 1471-2407

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