From: Artificial intelligence to guide precision anticancer therapy with multitargeted kinase inhibitors
Drug concentration | Panc 04.03 | DU 145 | HCC70 | |||
---|---|---|---|---|---|---|
JNJ-7706621 | PP1 | AZD6482 | XMD8–92 | GW2580 | PI-103 | |
1 nm | −1.000 / -0.596 | −1.000 / -0.771 | − 0.344 / -0.147 | − 0.791 / -0.998 | − 0.086 / -0.361 | 0.176 / -0.077 |
3.162 nm | −1.000 / -0.807 | − 1.000 / -0.830 | − 0.908 / -0.968 | − 0.892 / -0.992 | 0.129 / -0.040 | 0.042 / 0.036 |
10 nm | − 1.000 / -0.922 | − 1.000 / -0.697 | − 0.788 / -0.429 | − 0.929 / -0.998 | 0.245 / 0.022 | − 0.472 / -0.265 |
31.62 nm | −1.000 / -0.708 | − 1.000 / -0.257 | − 0.609 / -0.995 | − 0.962 / -0.996 | − 0.131 / -0.048 | − 0.274 / 0.176 |
100 nm | − 1.000 / -0.818 | − 0.999 / -0.908 | − 0.977 / -0.991 | − 0.840 / -0.999 | − 0.421 / 0.335 | 0.158 / -0.076 |
316.2 nm | −0.111 / -0.968 | − 1.000 / -0.759 | − 0.340 / -0.977 | − 0.557 / -0.976 | −0.116 / 0.556 | − 0.353 / -0.437 |
1 μm | − 0.570 / -0.982 | −1.000 / -0.838 | −0.581 / -0.982 | − 0.892 / -0.996 | 0.139 / 0.249 | 0.238 / -0.330 |
3.162 μm | −0.026 / -0.665 | −1.000 / -0.738 | −0.211 / -0.998 | − 0.799 / -0.993 | −0.206 / -0.345 | − 0.943 / -0.884 |
10 μm | − 0.188 / -0.723 | −1.000 / -0.739 | −0.987 / -0.995 | − 0.714 / -0.852 | −0.808 / -0.319 | − 0.985 / -0.797 |