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Table 6 Stratified association between mSIS and DFS by traditional biomarkers and pCR

From: Prognostic value of a modified systemic inflammation score in breast cancer patients who underwent neoadjuvant chemotherapy

Parameters

mSIS high risk

mSIS low risk

P value

P value for interaction

HR (95% CI)

  

ER

   

0.622

 negative

1 (reference)

0.741 (0.429–1.279)

0.282

 

 positive

1 (reference)

0.699 (0.423–1.152)

0.160

 

PR

   

0.530

 negative

1 (reference)

0.738 (0.449–1.215)

0.232

 

 positive

1 (reference)

0.699 (0.404–1.207)

0.199

 

HER-2

   

0.412

 negative

1 (reference)

0.519 (0.295–0.914)

0.023

 

 low expression

1 (reference)

0.729 (0.381–1.394)

0.339

 

 positive

1 (reference)

1.078 (0.504–2.304)

0.847

 

Ki-67

   

0.180

  ≤ 14%

1 (reference)

0.879 (0.442–1.749)

0.714

 

  > 14%

1 (reference)

0.641 (0.413–0.996)

0.048

 

pCR

   

0.004

 no

1 (reference)

0.722 (0.491–1.061)

0.097

 

 yes

1 (reference)

0.987 (0.275–3.540)

0.984

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