Parameters | mSIS high risk | mSIS low risk | P value | P value for interaction |
---|---|---|---|---|
HR (95% CI) | Â | Â | ||
ER | Â | Â | Â | 0.622 |
 negative | 1 (reference) | 0.741 (0.429–1.279) | 0.282 |  |
 positive | 1 (reference) | 0.699 (0.423–1.152) | 0.160 |  |
PR | Â | Â | Â | 0.530 |
 negative | 1 (reference) | 0.738 (0.449–1.215) | 0.232 |  |
 positive | 1 (reference) | 0.699 (0.404–1.207) | 0.199 |  |
HER-2 | Â | Â | Â | 0.412 |
 negative | 1 (reference) | 0.519 (0.295–0.914) | 0.023 |  |
 low expression | 1 (reference) | 0.729 (0.381–1.394) | 0.339 |  |
 positive | 1 (reference) | 1.078 (0.504–2.304) | 0.847 |  |
Ki-67 | Â | Â | Â | 0.180 |
  ≤ 14% | 1 (reference) | 0.879 (0.442–1.749) | 0.714 |  |
  > 14% | 1 (reference) | 0.641 (0.413–0.996) | 0.048 |  |
pCR | Â | Â | Â | 0.004 |
 no | 1 (reference) | 0.722 (0.491–1.061) | 0.097 |  |
 yes | 1 (reference) | 0.987 (0.275–3.540) | 0.984 |  |