Table 5 Stratified association between mSIS and OS by traditional biomarkers and pCR

ER

0.320

 negative

1 (reference)

0.628 (0.318–1.240)

0.180

 positive

1 (reference)

0.440 (0.248–0.780)

0.005

PR

0.161

 negative

1 (reference)

0.691 (0.373–1.278)

0.239

 positive

1 (reference)

0.377 (0.202–0.706)

0.002

HER-2

0.181

 negative

1 (reference)

0.397 (0.203–0.777)

0.007

 low expression

1 (reference)

0.381 (0.180–0.807)

0.012

 positive

1 (reference)

1.372 (0.477–3.949)

0.558

Ki-67

0.278

  ≤ 14%

1 (reference)

0.621 (0.266–1.450)

0.271

  > 14%

1 (reference)

0.510 (0.305–0.852)

0.010

pCR

0.033

 no

1 (reference)

0.491 (0.313–0.773)

0.002

 yes

1 (reference)

1.558 (0.195–12.47)

0.676