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Table 1 Characteristics of 78 patients with advanced hepatocellular carcinoma who received low-dose nivolumab

From: Low-dose nivolumab in advanced hepatocellular carcinoma

Characteristics

Age (median, range)

63 (38–81) years

Sex

 Male

61 (78.2%)

 Female

17 (21.8%)

ECOG PS

 0

34 (43.6%)

 1

44 (56.4%)

Child–Pugh classification

 A

58 (74.4%)

 B (7)

20 (25.6%)

BCLC classification

 C

78 (100%)

ALBI grade

 1

33 (42.3%)

 2

45 (57.7%)

Viral hepatitis status

 Hepatitis B

49 (62.8%)

 Hepatitis C

23 (29.5%)

 No

6 (7.7%)

Macrovascular invasion (IVC, HV, PV)

 Yes

39 (50%)

 No

39 (50%)

Main portal vein thrombosis

 Yes

11 (14.1%)

 No

67 (85.9%)

History of hepatectomy

 Yes

31 (39.7%)

 No

47 (60.3%)

Extrahepatic spread

 Yes

39 (50%)

 No

39 (50%)

Lymph node metastasis

 Yes

27 (34.6%)

 No

51 (65.4%)

AFP (median, range) ng/ml

523 (< 2.0 – > 80,000)

  1. ECOG PS Eastern Cooperative Oncology Group Performance Status, BCLC Barcelona-Clinic Liver Cancer, ALBI Albumin-Bilirubin, IVC Inferior vena cava, HV Hepatic vein, PV Portal vein, AFP Alpha-fetoprotein. All status mentioned above were determined at the time of nivolumab initiation