Circulating levels of IL-6 and TGF-β1 in patients with prostate cancer undergoing radiotherapy: associations with acute radiotoxicity and fatigue symptoms

Table 7 Correlations between acute genitourinary (GU) toxicity grade, acute gastrointestinal (GI) toxicity grade, fatigue score, and serum concentrations of IL-6 and TGF-β1 after the 25^th fraction in patients with prostate cancer treated with radiotherapy

Variable 1	Variable 2	Correlation coefficient	p
GU toxicity grade after the 25^th fraction	GI toxicity grade after the 25^th fraction	0.27	0.095
GI toxicity grade after the 25^th fraction	Fatigue score after the 25^th fraction	0.32	0.051
GU toxicity grade after the 25^th fraction	Fatigue score after the 25^th fraction	0.41	0.009
IL-6 concentration after the 25^th fraction	GU toxicity grade after the 25^th fraction	0.30	0.063
IL-6 concentration after the 25^th fraction	GI toxicity grade after the 25^th fraction	0.24	0.147
IL-6 concentration after the 25^th fraction	Fatigue score after the 25^th fraction	0.33	0.042
TGF-β1 concentration after the 25^th fraction	GU toxicity grade after the 25^th fraction	0.32	0.044
TGF-β1 concentration after the 25^th fraction	GI toxicity grade after the 25^th fraction	0.24	0.145
TGF-β1 concentration after the 25^th fraction	Fatigue score after the 25^th fraction	0.24	0.149

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