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Table 2 Clinicopathologic and US features of BC patients who presented with and without ALNM

From: Ultrasonography and clinicopathological features of breast cancer in predicting axillary lymph node metastases

Features

ALNM (n = 437) N (%)

Non-ALNM (n = 438) N (%)

P Value

Age(years)

 

0.009

  ≤ 50

224 (54.6%)

186 (45.4%)

 

  > 50

213 (45.8%)

252 (54.2%)

 

Histologic types

 

0.017

 Ductal

415 (51.1%)

397 (48.9%)

 

 Lobular

10 (47.6%)

11 (52.4%)

 

 Others

12 (28.6%)

30 (71.4%)

 

Histologic grades

 

0.000

 I

6 (14.0%)

37 (86.0%)

 

 II

199 (50.6%)

194 (49.4%)

 

 III

232 (52.8%)

207 (47.2%)

 

Molecular subtypes

 

0.000

 Luminal A

68 (37.4%)

114 (62.6%)

 

 Luminal B

194 (51.9%)

180 (48.1%)

 

 Luminal B HER2( +)

59 (72.0%)

23 (28.0%)

 

 HER2-enriched

62 (48.1%)

67 (51.9%)

 

 Triple negative

54 (50.0%)

54 (50.0%)

 

Multifocality

  

0.024

 Unifocal

349 (48.2%)

375 (51.8%)

 

 Multifocality

88 (58.3%)

63 (41.7%)

 

Tumor location

  

0.000

 Upper outer quadrant

294 (56.8%)

224 (43.2%)

 

 Others

143 (40.1%)

214 (59.9%)

 

Maximum diameter

  

0.000

  ≤ 2 cm

131 (39.9%)

197 (60.1%)

 

  > 2 cm

306 (55.9%)

241 (44.1%)

 

Shape

  

0.365

 Irregular

433 (50.1%)

431 (49.9%)

 

 Oval and round

4 (36.4%)

7 (63.6%)

 

Orientation

  

0.646

 Parallel

374 (50.3%)

370 (49.7%)

 

 Not parallel

63 (48.1%)

68 (51.9%)

 

Angular margin

  

0.665

 Yes

319 (50.4%)

314 (49.6%)

 

 No

118 (48.8%)

124 (51.2%)

 

Spiculated margin

  

0.000

 Yes

164 (63.1%)

96 (36.9%)

 

 No

273 (44.4%)

342 (55.6%)

 

Distance from the skin

  

0.000

  < 3 mm

109 (62.6%)

65 (37.4%)

 

  ≥ 3 mm

328 (46.8%)

373 (53.2%)

 
  1. Note. BC Breast cancer, ALNM Axillary lymph node metastasis, HER2 Human epidermal growth factor receptor 2