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Table 4 Overview of confirmed prognostic factor included in the meta-analysis

From: Prognostic markers in patients with chronic lymphocytic leukaemia on targeted therapy, chemoimmunotherapy with anti-CD20 monoclonal antibody: a systematic review and meta-analysis of prognostic factors

Prognostic factors

Studies

Pooled HR

Lower limit

Upper limit

I2(%)

References

Cytogenetic

 Deletion 17p

3

3.39

-0.21

6.99

90.84

[14, 17, 43]

 IGHV status

2

0.96

-0.07

1.99

94.02

[17, 53]

Protein factors

 β2 microglobulin

2

1.41

1.05

1.77

0

[17, 43]

  1. IGHV Immunoglobulin heavy variable gene, B2M β2-microglobulin