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Table 1 Working schedule of this study

From: Study protocol for artificial intelligence-assisted sponge cytology as pre-endoscopy screening for early esophegeal squmaous epithelial lesions in China

Time length

Activities

Expected stage outcomes

1st year

• Project announcement, planning and preparation

• Course training and project coordination

• Participant recruitment

• Cytological screening &endoscopy

• Data collection and transfer

• Scientific visit and supervision

♦ Project initiation

♦ Screening 4,000 participants from each site

2nd year

• Participant recruitment

• Cytological screening &endoscopy

• Data collection and transfer

• Scientific visit and supervision

♦ Screening 8,000 participants from each site

3rd year

• Participant recruitment

• Cytological screening &endoscopy

• Data collection

• Scientific visit and supervision

♦Screening 8,000 participants from each site

♦ Interim report

♦ Preparation of the first publication

4th year

• Participant recruitment

• Cytological screening &endoscopy

• Data collection

• Data verification and analysis

• Scientific conference

♦ Screening 4,000 participants from each site

♦ Data analysis

assessment of diagnostic efficiency

construction of prediction model

cost-efficiency analysis

5th year

• Participant recruitment

• Cytological screening &endoscopy

• Data analysis and archive

• Project summary

♦ Screening 2,000 participants from each site

♦ External validation

♦ Publication of results

♦ Dissemination of results to public health agencies