Table 2 Study measurements

Participant

Study ID, DOB^a, sex, ethnicity, NHS Lynch Syndrome genotype, local PI and participating NHS Trust.

FIT Data

Dates of participant mailings sent from the Southern Hub (baseline and years 1-3), FIT results (f-Hb for baseline and years 1-3.

Clinical^a

Date of colonoscopy at baseline and years 1-3 + follow-up years 4-6 for the subset of eligible patients, histological features and staging (where applicable) of biopsied specimen(s) at time of colonoscopy, anastomosis (Y/N), gastrointestinal (GI) comorbidities (Y/N), History of CRC (Y/N), date of CRC (where applicable), prior GI surgery (Y/N), GI surgery type (where applicable), other cancer(s) (Y/N), bowel prep quality, polyp retrieval (Y/N), colonoscopy key performance indicators (KPI) met (Y/N), aspirin use (Y/N), aspirin dosage (where applicable), additional medications (Y/N), additional medication details and dosage (where applicable).