Table 6 Categorization of irAEs
irAEs | No. (%) | Median days to onset | Grade of irAEs, n, 1/2/3/4 (%) |
|---|---|---|---|
Total | 29 (100) | 70 | 20 (68.97)/8 (27.59)/1 (3.44)/0 |
Hypothyroidism | 6 (20.69) | 94 | 5 (83.33)/1 (16.67)/0/0 |
Hyperthyroidism | 5 (17.24) | 92 | 2 (0.40)/3 (0.60)/0/0 |
Diarrhea/colitis | 3 (10.34) | 48 | 2 (66.67)/0/1 (33.33)/0 |
Rash | 3 (10.34) | 70 | 3 (100)/0/0/0 |
Myocardial enzyme increased | 3 (10.34) | 21 | 1 (33.33)/2 (66.67)/0/0 |
AST/ALT/Bilirubin increased | 2 (6.90) | 38.5 | 1 (50)/1 (50)/0/0 |
Creatinine increased | 2 (6.90) | 148.5 | 1 (50)/1 (50)/0/0 |
Myalgia | 1 (3.45) | 71 | 1 (100)/0/0/0 |
Pruritus | 1 (3.45) | 26 | 1 (100)/0/0/0 |
Thrombocytopenia | 1 (3.45) | 27 | 1 (100)/0/0/0 |
Hypohemoglobin | 1 (3.45) | 28 | 1 (100)/0/0/0 |
Fatigue | 1 (3.45) | 106 | 1 (100)/0/0/0 |