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Table 1 The relationship between FAM99A expression and clinical parameters in TCGA dataset

From: Liver-specific lncRNA FAM99A may be a tumor suppressor and promising prognostic biomarker in hepatocellular carcinoma

Clinical parameters

N

FAM99A expression

χ2

P

Low expression

High expression

Agea (years)

   

1.548

0.213

 ≤ 60

177

94

83

  

 > 60

193

90

103

  

Gender

   

0.006

0.941

 Male

250

125

125

  

 Female

121

60

61

  

Racea

   

1.286

0.257

 Asian

158

85

73

  

 Non-Asian

203

97

106

  

Hepatitis B virus infectiona

   

0.367

0.545

 Negative

248

120

128

  

 Positive

104

54

50

  

Hepatitis C virus infectiona

   

2.743

0.098

 Negative

296

152

144

  

 Positive

56

22

34

  

Vascular invasiona

   

15.688

< 0.001

 None

206

87

119

  

 Microvascular invasion

93

59

34

  

 Macrovascular invasion

16

12

4

  

Histological gradea

   

8.413

0.004

 G1-G2

232

102

130

  

 G3-G4

134

80

54

  

Pathological stagea

   

1.719

0.190

 I-II

257

125

132

  

 III-IV

90

51

39

  

T stagea

   

1.166

0.280

 I-II

275

133

142

  

 III-IV

93

51

42

  

N stagea

   

0.168

0.682

 N0

252

131

121

  

 N1

4

3

1

  

M stagea

   

0.184

0.668

 M0

266

137

129

  

 M1

4

3

1

  

Child-Pugh classification grade a

   

3.430

0.064

 A

217

103

114

  

 B+C

22

15

7

  
  1. Statistically significant P values are in bold (P < 0.05)
  2. Macro/micro Macrovascular invasion/microvascular invasion; TNM staging system according to the American Joint Committee on Cancer (AJCC) with T tumor, N lymph nodes metastasis, M distant metastasis
  3. a Represent have missing value