Table 2 Multiple comparison analysis of CRC cases diagnosed at CMJAH (2011–2015). Categorized by MSI status: MSI-L vs MSS vs MSI-H CRC and site: LCC vs RCC

Frequency/ Prevalence

303

30(10)

12(4)

160(53)

42(14)

12(4)

47(15)

GENDER

303

30

12

160

42

12

47

X² = 2.6877, df = 5

Male

160(53)

16(53)

6(50)

88(55)

24(57)

6(50)

20(43)

P = 0.748

Female

143(47)

14(47)

6(50)

72(45)

18(43)

6(50)

27(57)

No association of sex

AGE

303

29

12

160

42

12

47

FDR (q value = 0.8238) Q = 0.05

Min–Max

15–92

24–91

37–84

20–92

15–80

33–67

27–77

Mean ± SD

57 ± 14

56 ± 17

59 ± 13

58 ± 15

58 ± 13

50 ± 12

53 ± 14

E vs C: P = 0.0415*

Median

59

56

60

59

58

52

51

F vs C: P = 0.0274*

P25-P75 (IQR)

48–69

40–72

47–67

48–69

53–67

38–61

43–62

95% CI

[56-59]

[49-62]

[50–67]

[55-60]

[53-62]

[42-57]

[49-57]

ETHNIC GROUPS

303

30

12

160

42

12

47

X² = 9.2824, df = 5, P = 0.09832

Indigenous African

171(56)

22(76)

7(58)

83(47)

21(50)

10(83)

28(60)

A vs C: P = 0.0442*

Other Ethnic groups

132 (44)

8(24)

5(42)

77(53)

21(50)

2(17)

19(40)

E vs C: P = 0.0393*

AJCC TNM STAGING

178

9

8

76

37

7

41

X² = 7.6681, df = 5, P = 0.1755

I-II

77(43)

1(11)

4(50)

38(50)

12(32)

4(57)

18(44)

III-IV

101(57)

8(89)

4(50)

38(50)

25(68)

3(43)

23(56)

A vs C: P = 0.0348*

CROHN’S LIKE INFLAMMATORY RESPONSE

172

9

8

73

35

7

40

X² = 11.185, df = 5,P = 0.04782*

Mild-moderate

49(28)

6(67)

1(12)

19(26)

10(29)

4(57)

9(23)

A vs C: P = 0.0205*

Absent

123(72)

3(33)

7(88)

54(74)

25(71)

3(43)

31(77)

TUMOR INFILTRATING LYMPHOCYTES

178

15

8

73

35

7

40

X² = 12.898, df = 5, P = 0.02435*

D vs C: P = 0.0497*

Mild-moderate

68(38)

5(33)

2(25)

19(26)

16(46)

5(71)

21(52)

E vs C: P = 0.0231*

Absent

110(62)

10(67)

6(75)

54(74)

19(54)

2(29)

19(48)

F vs C: P = 0.0072**