Fig. 2

Identification of the two molecular subtypes based on P-DECRGs through consensus clustering in PTC. a CDF values and (b) Relative changes in the area under the CDF curve corresponding to different consensus matrices for K = from 2 to 10. c The consensus clustering matrix defining two clusters (K = 2) and their correlation area visualized using a heatmap. d Different transcriptional expressions between C1 and C2 analyzed by PCA. e A remarkable difference in DFS was observed between C1 and C2, which were visualized using a Kaplan–Meier plot. f The heatmap, g GO biological processes, h Cellular components, and (i) Molecular function enrichment analysis results of DEGs between C1 and C2 visualized using Circos. j KEGG enrichment analysis results of DEGs between C1 and C2 visualized using a bubble chart. PTC, papillary thyroid carcinoma; P-DECRGs, prognostic associated and differentially expressed cuproptosis-related genes; C1, cluster1; C2, cluster2; CDF, cumulative distribution function; PCA, principal components analysis; HR, hazard ratio; DEGs, differentially expressed genes; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes