Characteristics | Univariable analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
 | HR | 95% CI | P | HR | 95% CI | P |
Gender | 0.833 | 0.386–1.798 | 0.641 |  |  |  |
Age at diagnose (52) | 0.581 | 0.259–1.304 | 0.188 |  |  |  |
Multifocal | 2.340 | 1.078–5.079 | 0.032 * | 1.366 | 0.601–3.107 | 0.456 |
ETE | 2.961 | 1.315–6.666 | 0.009 * | 2.226 | 0.334–14.846 | 0.408 |
Bilateral lesions | 1.614 | 0.555–4.691 | 0.380 |  |  |  |
Tumor size | 1.680 | 0.933–3.026 | 0.084 |  |  |  |
pT stage | 1.545 | 1.113–2.143 | 0.009 * | 0.880 | 0.379–2.044 | 0.766 |
pN stage | 2.235 | 1.374–3.636 | 0.001 * | 1.371 | 0.540–3.482 | 0.007 * |
AJCC 8th TNM stage | 1.975 | 1.265–3.084 | 0.003 * | 1.186 | 0.494–2.847 | 0.702 |
Coexist HT | 1.745 | 0.412–7.389 | 0.450 |  |  |  |
Pathology | 0.821 | 0.541–1.246 | 0.353 |  |  |  |
IDO2 expression | 2.530 | 1.147–5.577 | 0.021 * | 1.562 | 0.639–3.823 | 0.328 |