Table 2 Univariable and multivariate Cox analysis for RFS in patients with MTC

Gender

0.833

0.386–1.798

0.641

Age at diagnose (52)

0.581

0.259–1.304

0.188

Multifocal

2.340

1.078–5.079

0.032 ^*

1.366

0.601–3.107

0.456

ETE

2.961

1.315–6.666

0.009 ^*

2.226

0.334–14.846

0.408

Bilateral lesions

1.614

0.555–4.691

0.380

Tumor size

1.680

0.933–3.026

0.084

pT stage

1.545

1.113–2.143

0.009 ^*

0.880

0.379–2.044

0.766

pN stage

2.235

1.374–3.636

0.001 ^*

1.371

0.540–3.482

0.007 ^*

AJCC 8th TNM stage

1.975

1.265–3.084

0.003 ^*

1.186

0.494–2.847

0.702

Coexist HT

1.745

0.412–7.389

0.450

Pathology

0.821

0.541–1.246

0.353

IDO2 expression

2.530

1.147–5.577

0.021 ^*

1.562

0.639–3.823

0.328