Skip to main content

Table 2 Factors associated with OS in the univariate and multivariate analyses

From: Prognostic impact of the number of metastatic lymph nodes after surgery in locally advanced hypopharyngeal cancer

Factors

Category

Univariate analysis

Multivariate analysis

  

HR

95% CI

p value

HR

95% CI

p value

Sex

Male vs. female

1.30

0.55–3.05

0.550

1.18

0.49–2.86

0.711

Age

≥ 65 years vs. <65 years

1.89

1.01–3.52

0.046

1.95

0.98–3.65

0.056

pT

pT1–2 vs. pT3–4

1.95

0.83–4.60

0.126

2.11

0.86–5.18

0.103

Number of pLNs

≥ 3 vs. 0–2

3.18

1.76–5.73

< 0.001

2.39

1.16–4.94

0.019

Adjuvant therapy

CRT vs. any

1.13

0.59–2.17

0.714

0.34

0.16–0.72

0.005

Positive ENE

Yes vs. no

3.66

2.01–6.67

< 0.001

4.60

2.26–9.36

< 0.001

Positive margin

Yes vs. no

1.18

0.50–2.76

0.071

0.55

0.22–1.36

0.193

  1.  h: hazard ratio, CI: confidence interval, pLNs: pathological metastatic lymph nodes, CRT: chemoradiotherapy, ENE: extranodal-extension