Fig. 3
From: NOVA1 promotes NSCLC proliferation and invasion by activating Wnt/β-catenin signaling
NOVA1 promoted proliferation and inhibited apoptosis in NSCLC cells. A The expression of NOVA1 was detected by western blotting in A549 and PC12 cells B The expression of NOVA1 was detected by western blotting in human bronchial epithelial cell line (HBE) and NSCLC cell lines (A549, H1299, H1650 and H827). C The mRNA levels of NOVA1 in A549 and H1299 cells transfected with siRNA negative control(siNC) and siNOVA1s, **P < 0 .01. D The protein levels of NOVA1 in A549 and H1299 cells transfected with siNC and siNOVA1s. E Cell viability was detected in A549 and H1299 cells transfected with siRNA negative control(siNC) and siNOVA1s. F The images of the colony formation assay in A549 and H1299 cells with or without siNOVA1s.The number of colonies formed by each group is shown in the histogram, **P < 0 .01. G The apoptosis of A549 and H1299 cells with or without siNOVA1s were examined by flow cytometer, **P < 0 .01; ***P < 0 .001