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Table 3 Association between inflammatory burden index and overall survival of patients with patients with colorectal cancer at 90-day outcome

From: Lymphocyte to C-reactive protein ratio could better predict the prognosis of patients with stage IV cancer

Variables

Model a

Model b

Model c

HR (95%CI)

p value

HR (95%CI)

p value

HR (95%CI)

p value

LCR

 Continuous (per SD)

0.525 (0.335,0.823)

0.005

0.54 (0.347,0.843)

0.007

0.56 (0.359,0.873)

0.011

 Cutoff value

 

 < 0.001

 

 < 0.001

 

 < 0.001

 C1 (< 2813.953)

ref

 

ref

 

ref

 

 C2 (≥ 2813.953)

0.252 (0.179,0.355)

 

0.281 (0.198,0.397)

 < 0.001

0.296 (0.209,0.42)

 

Quartiles

 Q1 (< 4.08)

ref

 

ref

 

ref

 

 Q2 (4.08–11.37)

0.344 (0.244,0.485)

 < 0.001

0.376 (0.265,0.533)

 < 0.001

0.390 (0.274,0.553)

 < 0.001

 Q3 (11.37–65.47)

0.23 (0.156,0.34)

 < 0.001

0.270 (0.182,0.401)

 < 0.001

0.284 (0.191,0.423)

 < 0.001

 Q4 (≥ 65.47)

0.145 (0.092,0.229)

 < 0.001

0.170 (0.107,0.270)

 < 0.001

0.183 (0.115,0.293)

 < 0.001

 p for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

  1. Model a: No adjusted
  2. Model b: Adjusted for age, sex, BMI, TNM stage
  3. Model c: Adjusted for age, sex, BMI, TNM stage, tumor type, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoking, drinking, family history
  4. HR Hazard ratio, 95%CI 95%confidence intervals, NLR Neutrophil-to-lymphocyte ratio