Fig. 4From: Liquid biopsy for detecting epidermal growth factor receptor mutation among patients with non-small cell lung cancer treated with afatinib: a multicenter prospective studya Kaplan–Meier curve of OS in patients expressing the T790M resistance gene at PD. The median OS of patients positive for T790M was not significantly different compared to negative patients (41.2 vs. 34 months, HR, 0.71; 95% CI 0.20–2.55; P = 0.603). b Kaplan–Meier curve of PFS in patients expressing the T790M resistance gene at PD. The median PFS of patients positive for T790M was not significantly different compared to negative patients (14.6 vs. 16 months, HR, 1.02; 95% CI 0.38–2.70; P = 0.972). CI, confidence interval; HR, hazard ratio; OS, overall survival; PFS, progression-free survival; PD, progressive diseaseBack to article page