Fig. 1
From: LRIG2 regulates cell proliferation, migration and apoptosis of osteosarcoma
The expressions of LRIG2 in osteosarcoma tissues and cell lines, and its correlation with patients’ prognosis. A IHC staining of LRIG2 in OS tissues and Para-cancerous tissues (100 × and 400 ×). B Statistical analysis of IHC staining of LRIG2 in human OS TMA. C qRT-PCR was performed to measure the expression of LRIG2 mRNA in different OS cells and osteoblastic cells, GAPDH was used as an internal reference. D Western blot was performed to measure the relative expression of LRIG2 protein in OS cell lines (MG63, 143B, HOS and U2) compared with human osteoblast cell line hFOB1.19. E Distribution of LRIG2 IHC staining scores in OS tissues according to Enneking stage classification. F GEPIA2 database analyzes the 5-year survival prognosis of LRIG2 in sarcoma patients