Fig. 4

Correlation between all variables under study in the entire cohort. Relationship between age, body mass index (BMI), Insulin, C-peptide, triglycerides (Trig), Total cholesterol (Chol), HDL-cholesterol (HDL-C), non-HDL cholesterol (non-HDL), LDL-cholesterol (LDL-C), apolipoprotein B100 (Apo B), ANGPTL3, lipoprotein (a) (Lp(a)), and PCSK9 were assessed in the entire cohort. A Matrix on the left represents Spearman Rho correlation coefficients. Dark grey is indicative either of a Rho coefficient close to + 1 (positive correlation) or a Rho coefficient closer to -1 (negative correlation). White indicates an absence of correlation (coefficient equal to 0). B Matrix on the right displays the corresponding p-value for each Rho coefficient on the left. As expected, C-peptide, insulin and triglycerides show a significant correlation with BMI scores. Other statistically significant correlations include: LDL-C and its core protein Apo B, non-HDL cholesterol and LDL-C, non-HDL cholesterol and Apo B levels. Neither PCSK9, ANGPTL3 nor lipoprotein (a) show significant correlation with the rest of the lipid panel components. ANGPTL3 levels, however, appear to be significantly associated, at least partially (Rho = 0.30), with age (p-value = 0.04, n = 46)