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Fig. 4 | BMC Cancer

Fig. 4

From: Interaction of miR-200a-3p with YAP regulates cell proliferation and metastasis differentially in HPV-positive and HPV-negative cervical cancer cells

Fig. 4

Differential responses of miR-200a-3p-YAP signal transduction to HPV-negative C33A and HPV16-positive Siha cells. Colony forming was promoted in C33A (A) but inhibited in Siha (B) with co-up-regulation of YAP and miR-200a-3p, respectively. EDU-positive cells were increased in C33A (C) but decreased in Siha (D) with co-up-regulation of YAP and miR-200a-3p, respectively. Cell migration and invasion were enhanced in C33A (E) but declined in Siha (F) with co-up-regulation of YAP and miR-200a-3p, respectively. 100 × Magnification. *p < 0.05, **p < 0.01, ***p < 0.001, ns: not significant

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