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Table 3 Enrichment of KEGG pathways in the NR1H4 high expression group

From: Clinical significance and oncogenic function of NR1H4 in clear cell renal cell carcinoma

No GS DETAILS SIZE ES NES NOM p-val FDR q-val
1 KEGG_N_GLYCAN_BIOSYNTHESIS 42 0.602 2.223 0.000 0.000
2 KEGG_PROTEASOME 38 0.578 1.949 0.000 0.000
3 KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 33 0.574 1.702 0.250 0.013
4 KEGG_CELL_CYCLE 100 0.537 1.763 0.000 0.016
5 KEGG_MISMATCH_REPAIR 19 0.625 1.848 0.000 0.020
6 KEGG_DNA_REPLICATION 32 0.640 1.876 0.000 0.027
7 KEGG_P53_SIGNALING_PATHWAY 59 0.622 1.581 0.000 0.095
8 KEGG_NUCLEOTIDE_EXCISION_REPAIR 37 0.569 1.582 0.000 0.107
9 KEGG_PROTEIN_EXPORT 19 0.614 1.552 0.000 0.116
10 KEGG_RENAL_CELL_CARCINOMA 59 0.513 1.584 0.000 0.122
11 KEGG_HOMOLOGOUS_RECOMBINATION 20 0.402 1.554 0.000 0.128
12 KEGG_BASAL_TRANSCRIPTION_FACTORS 26 0.539 1.509 0.000 0.141
13 KEGG_TYPE_II_DIABETES_MELLITUS 43 0.334 1.487 0.000 0.141
14 KEGG_CHRONIC_MYELOID_LEUKEMIA 62 0.463 1.485 0.000 0.143
15 KEGG_BLADDER_CANCER 37 0.573 1.492 0.000 0.150
16 KEGG_MTOR_SIGNALING_PATHWAY 46 0.424 1.488 0.000 0.150
17 KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS 17 0.634 1.522 0.000 0.152
18 KEGG_PANCREATIC_CANCER 64 0.509 1.523 0.000 0.164
19 KEGG_APOPTOSIS 81 0.470 1.451 0.200 0.230
20 KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 58 0.374 1.433 0.000 0.268
  1. Statistical data were performed by GSEA software
  2. Abbreviations: KEGG Kyoto encyclopedia of genes and genomes, ES Enrichment score, FDR q‐val False discovery rate q value, NES Normal enrichment score, NOM p‐val Nominal P‐value