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Table 3 Multiple logistic regression analysis on anthracycline-induced subclinical cardiotoxicity in DLBCL patients completed 3 cycles chemotherapy

From: Study on influencing factors of anthracycline-induced subclinical cardiotoxicity in DLBCL patients administered (R)-CHOP

Characteristics

OR (95%CI)

(Adjusted)

P-value

Age, per 1 year

1.053 (0.987, 1.124)

0.118

Male, yes versus no

3.212 (0.680, 15.185)

0.141

Smoking, yes versus no

2.601 (0.450, 15.016)

0.285

BMI, per 1 kg/m2

1.239 (0.967, 1.589)

0.090

NT-proBNP, per 1 ng/L

0.995 (0.988, 1.002)

0.179

e’, per 1 cm/s

2.045 (1.201, 3.481)

0.008

TG, per 1 mmol/L

2.810 (1.114, 7.088)

0.029

LDL-C, per 1 mmol/L

0.833 (0.315, 2.200)

0.712

ApoA1, per 1 g/L

0.032 (0.002, 0.611)

0.022

HDL-C, per 1 mmol/L

0.057 (0.003, 0.964)

0.047

  1. Age, gender, and variables with P < 0.10 in Table 2 (smoking history, BMI, NT-proBNP, e’, TG and LDL-C) were considered as potential cofounding factors
  2. Bold values indicate statistical significance (P < 0.05)
  3. ApoA1 Apolipoprotein A1, BMI Body mass index, DLBCL Diffuse large-B cell lymphoma, e’ mitral e’ velocity, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, NT-proBNP N terminal-pro brain natriuretic peptide, TG Total triglyceride, OR Odds ratio