Fig. 4From: ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancerEffect of AZD0156 and SN38 on effectors of DDR in CRC cell lines. Immunoblots showing effects of AZD0156 at doses of 50Â nM and 100Â nM and SN38 10Â nM alone and in combination on effectors of DDR and ATM activity at 24 and 72Â h. Experiments performed with 3 replicatesBack to article page