Fig. 2

Effect of AZD0156 and SN38 on cellular regrowth in CRC cell lines. Percent confluence of CRC cells following exposure to SN38 2.5 nM and AZD0156 at 50 nM and 100 mM doses alone or in combination, followed by incubation in drug-free media for 72 h. A HCT8, B RKO, C LOVO, D HT29. Experiments performed with 3 replicates. * = p ≤ 0.05,*** = p ≤ 0.001,**** = p ≤ 0.0001. ND = No Drug; SN38 = SN38 2.5 nM; AZD 50 = AZD0156 50 nM; AZD 100 = AZD0156 100 nM