Table 1 Patients characteristics according to the treatment group
Characteristics | All(%) | LINAC-SR(%) | WBRT(%) | WBRT + RTB (%) | P |
|---|---|---|---|---|---|
Number of patients | 156(100) | 77(49.4) | 44(28.2) | 35(22.4) | |
Sex | 0.350 | ||||
Female | 58(37.2) | 33(42.9) | 14(31.8) | 11(31.4) | |
Male | 98(62.8) | 44(57.1) | 30(68.2) | 24(68.6) | |
Age, years | 0.745 | ||||
≤ 50 | 57(36.5) | 30(39.0) | 16(36.4) | 11(31.4) | |
≥ 51 | 99(63.5) | 47(61.0) | 28(63.6) | 24(68.6) | |
Smoking history | 0.140 | ||||
No | 76(48.7) | 34(44.2) | 27(61.4) | 15(42.9) | |
Yes | 80(51.3) | 43(55.8) | 17(38.6) | 20(51.7) | |
KPS scores | 0.213 | ||||
≥ 90 | 96(61.5) | 46(59.7) | 28(63.6) | 22(62.9) | |
≤ 80 | 60(38.5) | 31(40.3) | 16(36.4) | 13(37.1) | |
Tumor histology | 0.056 | ||||
Squamous cell carcinoma | 22(14.1) | 16(20.8) | 4(9.1) | 2(5.7) | |
Adenocarcinoma | 134(85.9) | 61(79.2) | 40(90.9) | 33(94.3) | |
Thoracic operation | 0.784 | ||||
Yes | 68(43.6) | 32(41.6) | 19(43.2) | 17(48.6) | |
No | 88(56.4) | 45(58.4) | 25(56.8) | 18(51.4) | |
Initial treatment of BMs a | 0.628 | ||||
Yes | 66(42.3) | 30(39.0) | 19(43.2) | 17(48.6) | |
No | 90(57.7) | 47(61.0) | 25(56.8) | 18(51.4) | |
Neurologic symptoms | 0.613 | ||||
Yes | 69(44.2) | 32(41.6) | 19(43.2) | 18(51.4) | |
No | 87(55.8) | 45(58.4) | 25(56.8) | 17(48.6) | |
Number of BMs | 0.758 | ||||
1 | 91(58.3) | 45(58.4) | 24(54.5) | 22(62.9) | |
2–4 | 65(41.7) | 32(41.6) | 20(45.5) | 13(37.1) | |
BM size, Dmax (cm) | 0.167 | ||||
≤ 3 | 130(83.3) | 68(88.3) | 33(75.0) | 29(82.9) | |
> 3 | 26(16.7) | 9(11.7) | 11(25.0) | 6(17.1) | |
Primary disease control | 0.003 | ||||
Yes | 125(80.1) | 70(90.9) | 29(65.9) | 26(74.3) | |
No | 31(19.9) | 7(9.1) | 15(34.1) | 9(25.7) | |
EMs | 0.985 | ||||
Yes | 76(48.7) | 38(49.4) | 21(47.7) | 17(48.6) | |
No | 80(51.3) | 39(50.6) | 23(52.3) | 18(51.4) | |
RPA class | 0.902 | ||||
1 | 52(33.3) | 27(35.1) | 14(31.8) | 11(31.4) | |
2 | 104(66.7) | 50(64.9) | 30(68.2) | 24(68.6) | |
GPA scores | 0.411 | ||||
0.5–1.5 | 22(14.1) | 8(10.4) | 8(18.2) | 6(17.1) | |
2–2.5 | 62(39.7) | 33(42.9) | 19(43.2) | 10(28.6) | |
≥ 3 | 72(46.2) | 36(46.8) | 17(38.6) | 19(54.3) | |
Concurrent chemotherapy | 0.294 | ||||
Yes | 42(26.9) | 25(32.5) | 10(22.7) | 7(20.0) | |
No | 114(73.1) | 52(67.5) | 34(77.3) | 28(80.0) | |
TT after BMs | 0.091 | ||||
Yes | 47(30.1) | 17(22.1) | 16(36.4) | 14(40.0) | |
No | 109(69.9) | 60(77.9) | 28(63.6) | 21(60.0) |