The impact of age on rectal cancer treatment, complications and survival

BMC Cancer

Table 3 Logistic regression results identified factors associated with death within 90 days for all patients diagnosed with rectal cancer in 1980-2016

Factor	Death within 90 days, N/total	Unadjusted odds ratio (95% CI)	p value	Adjusted odds ratio (95% CI)	p value
Age (years)
<65	11/193 (7%)	1 (reference)		1 (reference)
65 - 79	32/329 (9.7%)	1.78 (0.88 to 3.62)	0.11	1.31 (0.58 to 2.97)	0.51
80+	22/144 (15.3%)	2.98 (1.40 to 6.37)	0.005	1.12 (0.43 to 2.91)	0.82
Calendar year		0.96 (0.94 to 0.99)	0.003	0.94 (0.91 to 0.97)	<0.001
ASA score					<0.001
1-2	23/402 (5.7%)	1 (reference)		1 (reference)
3	28/235 (11.9%)	2.23 (1.25 to 3.97)	0.006	1.64 (0.81 to 3.29)	0.17
4-5	14/29 (48.3%)	15.38 (6.63 to 35.67)	<0.001	4.18 (1.40 to 12.50)	0.01
Emergency surgery	4/27 (14.8%)	1.68 (0.56 to 5.01)	0.36	1.04 (0.27 to 4.05)	0.95
Treatment intent categories
Curative intent
Major resection	14/433 (3.2%)	1 (reference)		1 (reference)
Polypectomy	0/41	1		1
Non-curative intent
Major resection	5/58 (8.6%)	2.82 (0.98 to 8.15)	0.055	2.16 (0.73 to 6.4)	0.16
Bypass, stoma	14/47 (29.8%)	12.70 (5.59 to 28.86)	<0.001	11.11 (4.46 to 27.66)	<0.001
Best supportive care	32/87 (36.8%)	17.41 (8.75 to 34.65)	<0.001	15.99 (7.21 to 35.44	<0.001

Logistic regression was performed with death within 90 days as the dependent variable. Unadjusted was performed with one covariate at a time; adjusted was performed with all the listed covariates simultaneously

ISSN: 1471-2407