An experimental model for ovarian cancer: propagation of ovarian cancer initiating cells and generation of ovarian cancer organoids

Table 2 OCT4, SOX2 and NANOG expression in OC tumor tissues

Parameters (n = 18)	OCT4^high	OCT4^low	SOX2^high	SOX2^low	NANOG^high	NANOG^low
Tumor tissue (%)	12 (67)	6 (33)	13 (72)	5 (28)	5 (28)	13 (72)

Data are presented as counts (percentage). The histological score (HSCORE) ranged from 0 to 3 and was calculated to assess immunohistochemical staining by the following formula: HSCORE = ΣPi(i) where “pi” represents the percentage of positive cell counts in total cell counts, and “i” represents the intensity). An HSCORE of 0.05 was considered as a threshold to distinguish high expression and low expression

ISSN: 1471-2407