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Fig. 4 | BMC Cancer

Fig. 4

From: MiR-659-3p inhibits osteosarcoma progression and metastasis by inhibiting cell proliferation and invasion via targeting SRPK1

Fig. 4

MiR-659-3p inhibits osteosarcoma cells cell cycle from G1/G0 to S phase transition. A Transfection of miR-659-3p mimic in HOS osteosarcoma cells, increased G1/G0 phase cells from 54.7% to 67.1%. B Transfection of miR-659-3p inhibitor in Saos-2 cells decreased G1/G0 phase cells from 53.8% to 42.7%. C. Representative FACS plot showed the increase and decrease percentage of G1/G0 phase cells after transfection with miR-659-3p mimic or inhibitor compared to scramble control. ** indicates P < 0.01 and *** indicates P < 0.001 compared to scramble control

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