Tolerance to oral anticancer agent treatment in older adults with cancer: a secondary analysis of data from electronic health records and a pilot study of patient-reported outcomes

Table 2 The severity of capecitabine side effects by age groups and data sources

Severity of Side Effects	Age < 65 years old (n = 54)	Age \(\ge 65\) years old (n = 43)	p	EHR Sample (n = 47)	Patient-Reported Outcome Sample (n = 50)	p
Severity of Side Effects	Mean (SD)	Mean (SD)	p	Mean (SD)	Mean (SD)	p
Nausea	0.81 (1.03)	0.51 (0.77)	.13	0.53 (0.62)	0.78 (1.04)	.56
Vomiting	0.43 (0.90)	0.14 (0.41)	.07	0.26 (0.61)	0.32 (0.77)	.88
Diarrhea	0.81 (1.07)	0.83 (1.03)	.86	0.50 (0.86)	1.08 (1.03)	.002
HFS	0.31 (0.72)	0.79 (1.10)	.02	0.40 (0.82)	0.60 (0.90)	.20
Fatigue	0.89 (0.96)	1.44 (0.96)	.005	0.72 (0.88)	1.52 (0.95)	< .001
Constipation	0.59 (1.06)	0.72 (1.03)	.40	0.26 (0.57)	0.96 (1.11)	< .001
Mouth sores	0.22 (0.66)	0.40 (0.73)	.08	0.21 (0.62)	0.38 (0.75)	.12
Sleep difficulties	0.43 (0.79)	0.33 (0.64)	.59	0.04 (0.29)	0.70 (0.86)	< .001

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