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Table 4 Autoantibody against SPP1 in the diagnosis of ESCC

From: Serum anti-SPP1 autoantibody as a potential novel biomarker in detection of esophageal squamous cell carcinoma

Cohorts

AUC

95%CI

Se

(%)

Sp (%)

YI

PLR

NLR

PPV (%)

NPV (%)

Accuracy (%)

Discovery group

0.653

0.556–0.750

45.16

83.87

0.29

2.8

0.65

73.68

60.47

64.52

Validation group

0.739

0.671–0.807

41.00

87.00

0.28

3.15

0.68

75.93

59.59

64.00

  1. AUC Area under the curve, CI Confidence interval, Se Sensitivity, Sp Specificity, YI Youden index, PLR Positive likelihood ratio, NLR Negative likelihood ratio, PPV Positive predictive value, NPV Negative predictive value