Fig. 2

LncRNA XIST was upregulated in PCa tissues, and cell lines can promote the proliferation and invasion of PCa cells. A VCaP cells were transfected with NC or Ad-XIST for 72 h. The expression of lncRNA XIST in transfected VCaP cells was detected by qRT-PCR. B 22Rv1 cells were transfected with NC, XIST-shRNA1 or XIST-shRNA2 for 72 h. The level of XIST in 22Rv1 cells was detected by qRT‒PCR. **P<0.01 vs NC group. C VCaP cells were transfected with NC or Ad-XIST for 24, 48 and 72 h. The cell viability in transfected VCaP cells was detected by CCK8 assay. D VCaP cells were transfected with NC or Ad-XIST for 72 h. Relative fluorescence expression levels were quantified by Ki67 and DAPI staining. E VCaP cells were transfected with NC or Ad-XIST for 24 h. The cell migration in transfected VCaP cells was detected by transwell assay. **P<0.01 vs. NC group