Fig. 5
From: The expression of Hexokinase 2 and its hub genes are correlated with the prognosis in glioma
The correlation between HK2 expression and immune infiltration level in LGG and GBM. A Evaluation of the correlation between HK2 expression and immune infiltration by using the TIMER 2.0 database. B-E The correlation between the expression (B-C) or DNA methylation (D-E) of HK2 expression and immune infiltration in LGG and GBM specimens from the GSCA database. F The correlation between the expression of HK2 and immune score in gliomas. G The correlation between HK2 and the confirmed immune checkpoints in gliomas. H The mRNA levels of TNF-α, IL-2, IL-3, IL-4, and IL-12 in HK2-knockdown and control groups in T98 and GBM1 cell lines. Data are shown as mean ± SEM. *P < 0.05, **P < 0.01, ****P < 0.0001, ns, not significant