From: Prognostic significance and immune characteristics of CMTM4 in hepatocellular carcinoma
Variables | CMTM4 | PD-L1 | ||||||
---|---|---|---|---|---|---|---|---|
n | High | Low | P value | n | High | Low | P value | |
Age (years)a | Â | Â | Â | 0.085 | Â | Â | 0.880 | |
  < 60 | 68 | 36 | 32 |  | 63 | 14 | 49 |  |
  ≥ 60 | 22 | 7 | 15 |  | 21 | 5 | 16 |  |
Gender | Â | Â | Â | 0.881 | Â | Â | 0.310 | |
 Male | 80 | 38 | 42 |  | 74 | 18 | 56 |  |
 Female | 10 | 5 | 5 |  | 10 | 1 | 9 |  |
HBV | Â | Â | Â | 0.259 | Â | Â | 0.473 | |
 Positive | 70 | 36 | 34 |  | 66 | 14 | 52 |  |
 Negative | 19 | 7 | 12 |  | 17 | 5 | 12 |  |
AFP (ng/mL) | Â | Â | Â | 0.045 | Â | Â | 0.456 | |
  < 400 | 57 | 23 | 34 |  | 54 | 11 | 43 |  |
  ≥ 400 | 32 | 20 | 12 |  | 29 | 8 | 21 |  |
Cirrhosis | Â | Â | Â | 0.401 | Â | Â | 0.578 | |
 Yes | 80 | 40 | 40 |  | 74 | 11 | 43 |  |
 No | 9 | 3 | 6 |  | 9 | 8 | 21 |  |
Cirrhosis number | Â | Â | Â | 0.196 | Â | Â | 0.477 | |
  < 3 | 56 | 30 | 26 |  | 51 | 13 | 38 |  |
  ≥ 3 | 33 | 13 | 20 |  | 32 | 6 | 26 |  |
Tumor number | Â | Â | Â | 0.261 | Â | Â | 0.250 | |
 Single | 79 | 36 | 43 |  | 73 | 18 | 55 |  |
 Multiple | 11 | 4 | 7 |  | 11 | 1 | 10 |  |
Tumor sizeb | Â | Â | Â | 0.329 | Â | Â | 0.898 | |
  < 5 cm | 56 | 29 | 27 |  | 52 | 12 | 40 |  |
  ≥ 5 cm | 34 | 14 | 20 |  | 32 | 7 | 25 |  |
Differentiation | Â | Â | Â | 0.202 | Â | Â | 0.112 | |
 Well | 44 | 18 | 26 |  | 40 | 6 | 34 |  |
 Moderate-poor | 46 | 25 | 21 |  | 44 | 13 | 31 |  |
TNM stage | Â | Â | Â | 0.334 | Â | Â | 0.198 | |
 I | 63 | 28 | 35 |  | 61 | 16 | 45 |  |
 II-IV | 27 | 15 | 12 |  | 23 | 3 | 20 |  |
Tumor capsule | Â | Â | Â | 0.330 | Â | Â | 0.040 | |
 Complete | 42 | 18 | 24 |  | 38 | 15 | 30 |  |
 Incomplete | 47 | 25 | 22 |  | 45 | 4 | 34 |  |
TB (μmol/L) |  |  |  | 0.679 |  |  | 0.027 | |
  < 14.053 | 56 | 28 | 28 |  | 52 | 16 | 36 |  |
  ≥ 14.053 | 33 | 15 | 18 |  | 31 | 3 | 28 |  |
ALT (U/L) | Â | Â | Â | 0.996 | Â | Â | 0.436 | |
  < 48.360 | 60 | 29 | 31 |  | 55 | 14 | 41 |  |
  ≥ 48.360 | 29 | 14 | 15 |  | 28 | 5 | 23 |  |
ALB (g/L) | Â | Â | Â | 0.742 | Â | Â | 0.077 | |
  < 4.296 | 43 | 20 | 23 |  | 42 | 13 | 29 |  |
  ≥ 4.296 | 46 | 23 | 23 |  | 41 | 6 | 35 |  |
GGT (U/L) | Â | Â | Â | 0.809 | Â | Â | 0.51 | |
  < 77.101 | 61 | 30 | 31 |  | 56 | 14 | 42 |  |
  ≥ 77.101 | 28 | 13 | 15 |  | 27 | 5 | 22 |  |
CD4 expression | Â | Â | Â | 0.451 | Â | Â | 0.228 | |
 Low | 20 | 6 | 14 |  | 54 | 10 | 44 |  |
 High | 70 | 37 | 33 |  | 30 | 9 | 21 |  |
CD8 expression | Â | Â | Â | 0.847 | Â | Â | 0.001 | |
 Low | 21 | 11 | 10 |  | 41 | 3 | 38 |  |
 High | 69 | 32 | 37 |  | 43 | 16 | 27 |  |