Table 1 Baseline CRLM characteristics stratified by histopathological growth pattern
Non-desmoplastic | Desmoplastic | ||||
|---|---|---|---|---|---|
missing (%) | n = 152 (%) | n = 31 (%) | p-value | ||
Age at resection CRLM—(median [IQR]) | 66.5 [59.0, 74.0] | 68.0 [62.0, 76.5] | 0.26 | ||
Gender | Male | 55 (36) | 9 (29) | 0.45 | |
Female | 97 (64) | 22 (71) | |||
Resection timing | Liver first | 1 (1) | 0 (0) | 0.07 | |
Primary first | 141 (93) | 25 (81) | |||
Synchronous | 10 (7) | 6 (19) | |||
Metastasis timinga | Metachronous | 103 (68) | 16 (52) | 0.09 | |
Synchronous | 49 (32) | 15 (48) | |||
Disease-free interval in monthsa—(median [IQR]) | 12.0 [0.0, 24.2] | 4.0 [0.0, 20.5] | 0.11 | ||
Adjuvant CTx following CRC resectionb | No | 57 (55) | 13 (81) | 0.05 | |
Yes | 46 (45) | 3 (19) | |||
CRLM distribution | Unilobar | 127 (84) | 28 (90) | 0.34 | |
Bilobar | 25 (16) | 3 (10) | |||
Number of CRLM—(median [IQR]) | 1 (1) | 1.0 [1.0, 2.0] | 1.0 [1.0, 2.0] | 0.50 | |
Diameter of largest CRLM in cm—(median [IQR]) | 1 (1) | 3.2 [2.2, 4.1] | 2.0 [1.3, 3.0] | < 0.001 | |
Preoperative CEA in µg/L—(median [IQR]) | 13 (7) | 12.0 [5.0, 44.7] | 5.7 [3.2, 10.6] | 0.002 | |
Concomitant ablation | No | 134 (88) | 27 (87) | 0.66 | |
RFA | 15 (10) | 4 (13) | |||
MWA | 3 (2) | 0 (0) | |||
Resection margin involved | No | 4 (2) | 134 (91) | 31 (100) | 0.07 |
Yes | 14 (9) | 0 (0) | |||
Extrahepatic disease | No | 136 (89) | 30 (97) | 0.20 | |
Yes | 16 (11) | 1 (3) | |||